Top Missouri Hospitals 2025

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Rank Hospital Score City PROMs Patient Satisfaction Award
1 Barnes – Jewish Hospital 92.95% St. Louis ✓ ✓
2 Saint Luke’s Hospital of Kansas City 92.32% Kansas City ✓ ✓
3 Mercy Hospital St. Louis 86.46% St. Louis
4 St. Lukes Hospital 82.77% Chesterfield ✓
5 Boone Hospital Center 80.88% Columbia

 

1.Barnes – Jewish Hospital

Barnes-Jewish Hospital is the largest hospital in Missouri and serves as the adult teaching hospital for Washington University School of Medicine. Located in the Central West End neighborhood of St. Louis, it is a key component of the Washington University Medical Center and a flagship member of BJC HealthCare WikipediaBarnes-Jewish Hospital.​

🏥 Hospital Overview

With over 1,400 beds, Barnes-Jewish Hospital is a nonprofit teaching hospital renowned for its comprehensive medical services and commitment to patient care .​WashU Medicine Physicians

🩺 Medical Services & Specialties

Barnes-Jewish Hospital offers a wide array of medical services and specialties, including:​

  • Cardiology & Heart Surgery: Advanced treatments for heart conditions.

  • Neurology & Neurosurgery: Comprehensive care for neurological disorders.

  • Orthopedics: Treatment for musculoskeletal conditions.

  • Cancer Care: Multidisciplinary oncology services.

  • Obstetrics & Gynecology: Women’s health services.

  • Gastroenterology: Digestive system care.

  • Pulmonology: Lung and respiratory care.

  • Nephrology: Kidney-related treatments.

  • Emergency Medicine: 24/7 emergency care services.

  • Palliative Care: Supportive care for serious illnesses.

  • Rehabilitation Services: Physical, occupational, and speech therapies.

  • Transplant Services: Organ and tissue transplantation programs.​

The hospital is also recognized as a Level I Trauma Center, providing the highest level of emergency care .​Barnes-Jewish Hospital

🏆 Awards & Recognition

Barnes-Jewish Hospital has received numerous accolades, including:​

  • U.S. News & World Report Rankings: Ranked nationally in 11 adult specialties and rated high performing in 16 adult procedures and conditions .

  • Magnet Recognition: The first adult hospital in Missouri to receive Magnet designation for nursing excellence, with redesignations every five years since 2003 .

  • Leader in LGBTQ Healthcare Equality: Recognized by the Human Rights Campaign Foundation for inclusive care .

  • Level 4 Epilepsy Center: Designated by the National Association of Epilepsy Centers for providing the most comprehensive forms of intensive neurodiagnostic monitoring and treatment .​thetelegraph.com+2Health US News+2Saint Luke’s Health System Kansas City+2Barnes-Jewish Hospital

For more information or to schedule an appointment, please visit the official website: barnesjewish.org​Barnes-Jewish Hospital

2.Saint Luke’s Hospital of Kansas City

Saint Luke’s Hospital of Kansas City is a 600-bed, non-profit, faith-based tertiary care hospital located at 4401 Wornall Road in Kansas City, Missouri. Established in 1882, it serves as a key facility within the Saint Luke’s Health System and is affiliated with the University of Missouri–Kansas City and Saint Luke’s College of Nursing and Health Sciences .​Wikipedia+1PracticeMatch+1

🩺 Medical Services & Specialties

Saint Luke’s Hospital offers a wide array of medical services and specialties, including:​

  • Cardiology & Cardiothoracic Surgery

  • Neurology & Neurosurgery

  • Oncology/Hematology

  • Gastroenterology & GI Surgery

  • Orthopedics

  • Endocrinology, Diabetes, and Metabolism

  • ENT/Otolaryngology

  • Hepatology

  • Kidney & Liver Transplant

  • Maternity Care with Level IIIb NICU

  • Pain Management

  • Plastic Surgery

  • Psychiatry

  • Pulmonology

  • Rehabilitation Services

  • Primary Care

  • Emergency Department with Level I Trauma Center ​

🏆 Awards & Recognition

Saint Luke’s Hospital has received numerous accolades, including:​

For more information or to schedule an appointment, please visit the official website: saintlukeskc.org​

3.Mercy Hospital St. Louis

Mercy Hospital St. Louis is a 795-bed, non-profit, faith-based tertiary care hospital located at 615 South New Ballas Road in Creve Coeur, Missouri. As part of the Mercy health system, it serves patients across Missouri and neighboring states, offering a wide range of medical services and specialties. ​American Hospital Directory

🩺 Medical Services & Specialties

Mercy Hospital St. Louis provides comprehensive medical services, including:​

  • Cardiology & Heart Surgery

  • Neurology & Neurosurgery

  • Oncology & Hematology

  • Gastroenterology & GI Surgery

  • Orthopedics

  • Endocrinology & Diabetes Care

  • Nephrology

  • Pulmonology

  • Obstetrics & Gynecology

  • Pediatrics, including Pediatric Oncology

  • Burn Care

  • Stroke Care

  • Behavioral Health

  • Home Health & Hospice Services ​

The hospital is designated as a Level I Trauma Center and operates a Level III Neonatal Intensive Care Unit (NICU), providing the highest level of emergency and neonatal care in St. Louis County. ​WAAI

🏆 Awards & Recognition

Mercy Hospital St. Louis has received numerous accolades, including:​

  • HIMSS Stage 7 Recognition: Acknowledged for advanced electronic health record (EHR) integration, placing it among the most technologically advanced hospitals in the U.S. ​Wikipedia

  • American Heart Association’s Get With The Guidelines® Awards: Recognized for excellence in stroke care, adhering to nationally recognized, research-based treatment guidelines. ​Mercy Health Foundation

  • 2022 Excellence in Patient Experience Award: Named the top large health system in the U.S. for patient experience by NRC Health. ​PR Newswire

  • ACCC Innovator Award: Mercy Oncology Services honored for innovative approaches in cancer care. ​/+1Mercy+1

  • Women’s Choice Awards: Recognized in categories such as Obstetrics, Cancer Care, Bariatrics, Mammogram Imaging Center, and Women’s Services. ​Women’s Choice Award

For more information or to schedule an appointment, please visit the official website: www.mercy.net​Mercy+4Mercy+4Mercy+4

4.St. Lukes Hospital

Established in 1882, Saint Luke’s Hospital of Kansas City is a non-profit, faith-based tertiary care hospital. It is part of the Saint Luke’s Health System and serves as a teaching hospital affiliated with the University of Missouri–Kansas City and Saint Luke’s College of Nursing and Health Sciences. ​Wikipedia

🩺 Medical Services & Specialties

The hospital offers a wide range of medical services, including:​

With over 600 physicians representing more than 60 medical specialties, the hospital provides comprehensive care to patients. ​Saint Luke’s Health System Kansas City+1LinkedIn+1

🏥 St. Luke’s Hospital – Chesterfield, Missouri

Founded in 1866, St. Luke’s Hospital in Chesterfield is an independent, non-profit healthcare provider serving the greater St. Louis area. The hospital operates a 493-bed facility and offers services across more than 60 specialties. ​YouTube+2LinkedIn+2Wikipedia+2

🩺 Medical Services & Specialties

St. Luke’s Hospital provides a variety of medical services, including:​

  • Cardiology (affiliated with Cleveland Clinic’s Heart and Vascular Institute)

  • Neurology & Neurosurgery

  • Oncology & Hematology

  • Gastroenterology & GI Surgery

  • Orthopedics

  • Endocrinology & Diabetes Care

  • Nephrology

  • Pulmonology

  • Obstetrics & Gynecology

  • Pediatrics

  • Emergency Medicine​Wikipedia

In 2018, St. Luke’s Hospital expanded its services by acquiring the nearby Des Peres Hospital. ​Wikipedia+1LinkedIn+1

If you have a specific location or service in mind, feel free to let me know, and I can provide more detailed information.

5.Boone Hospital Center

Boone Hospital Center is a 394-bed, county-owned, non-profit hospital located at 1600 E. Broadway in Columbia, Missouri. Established in 1921, it serves as a regional referral center, providing comprehensive healthcare services to 25 Mid-Missouri counties. With over 2,000 employees, it stands as one of the largest employers in Columbia. ​Wikipedia+1LinkedIn+1

🩺 Medical Services & Specialties

Boone Hospital Center offers a wide array of medical services and specialties, including:​

  • Cardiology & Heart Surgery

  • Neurology & Neurosurgery

  • Oncology/Hematology

  • Orthopedics

  • Gastroenterology

  • Endocrinology & Diabetes Care

  • Pulmonology

  • Nephrology

  • Obstetrics & Gynecology

  • Pediatrics

  • Emergency Medicine

  • Primary Care

  • Occupational Therapy

  • Surgical Services: Specializing in cardiovascular and thoracic, plastic, orthopedic, vascular, ophthalmologic, urologic, oral, neurologic, otolaryngologic, dental, gynecologic, and general surgery. ​Boone Health –

The hospital is designated as a Level I Stroke and STEMI Center, ensuring the highest level of emergency care for stroke and heart attack patients. ​Wikipedia

🏆 Awards & Recognition

Boone Hospital Center has received numerous accolades, including:​

  • Magnet Recognition: Achieved its fifth consecutive Magnet designation from the American Nurses Credentialing Center, highlighting excellence in nursing.

  • Healthgrades Awards:

    • America’s 100 Best Hospitals Award™ (2023, 2024, 2025)

    • America’s 250 Best Hospitals Award™ (2023, 2024, 2025)

    • Patient Safety Excellence Award™ (2023, 2024)

    • Outstanding Patient Experience Award™ (2022)

    • Surgical Care Excellence Award™ (2023)

    • America’s 100 Best Hospitals for Spine Surgery Award™ (2025)

    • America’s 50 Best Hospitals for Outpatient Joint Replacement Award™ (2025)

    • America’s 50 Best Hospitals for Outpatient Orthopedic Surgery Award™ (2025)

    • Joint Replacement Excellence Award™ (2025)

    • America’s 100 Best Hospitals for Joint Replacement Award™ (2023, 2024) ​Boone Health –+1Wikipedia+1Healthgrades

For more information or to schedule an appointment, please visit the official website: boone.health​Boone Health –

Read more:

  1. Top Mississippi Hospitals 202
  2. Top Minnesota Hospitals 2025
  3. Top Michigan Hospitals 2025
  4. Top Massachusetts Hospitals 2025
  5. America’s Best-In-State Hospitals in Washington, D.C.

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